CALL FOR PAPERS Endothelins Endothelin and calciotropic hormones share regulatory pathways in multidrug resistance protein 2-mediated transport
نویسندگان
چکیده
Kim E. Wever, Rosalinde Masereeuw, David S. Miller, Xiao M. Hang, and Gert Flik Department of Animal Physiology, Institute for Neuroscience Faculty of Science, Radboud University Nijmegen, and Department of Pharmacology and Toxicology, Nijmegen Centre for Molecular Life Sciences/Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands; 3 Mount Desert Island Biological Laboratory, Salisbury Cove, Maine; Laboratory of Pharmacology and Chemistry, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina; Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom; and Institute of Environmental Systems Biology, Dalian Maritime University, Dalian, China
منابع مشابه
Endothelin and calciotropic hormones share regulatory pathways in multidrug resistance protein 2-mediated transport.
The kidney of vertebrates plays a key role in excretion of endogenous waste products and xenobiotics. Active secretion in the proximal nephron is at the basis of this excretion, mediated by carrier proteins including multidrug resistance protein 2 (Mrp2). We previously showed that Mrp2 function is reduced by endothelin-1 (ET-1) through a basolateral B-type receptor, nitric oxide (NO), cGMP, and...
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تاریخ انتشار 2006